ABMIUM target intelligence

PTPRC

protein tyrosine phosphatase receptor type C

PTPRC identifies protein tyrosine phosphatase receptor type C in Homo sapiens (Human). This target record connects NCBI Gene 5788, UniProtKB P08575 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene5788 UniProtP08575

ABMIUM research catalogue

Research Products

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Research context & evidence

About PTPRC

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

PTPRC (CD45) is a receptor-type protein tyrosine phosphatase and an essential regulator of T-cell and B-cell antigen-receptor signalling. It can regulate Src-family kinases and cytokine-receptor signalling.

Experimental context

Research context

PTPRC is studied in leukocyte identity, lymphocyte activation, antigen-receptor signalling and immune-cell phenotyping, including CD45 isoform biology.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

CD45Receptor-type tyrosine-protein phosphatase CB220CD45RGP180IMD105L-CALY5T200Lyt-4locRT7