ABMIUM target intelligence
glucagon
GCG identifies glucagon in Homo sapiens (Human). This target record connects NCBI Gene 2641, UniProtKB P01275 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
GCG encodes proglucagon, a secreted precursor that is processed in a tissue-specific manner into biologically active peptides including glucagon, GLP-1, GLP-2, oxyntomodulin and glicentin-related products. Glucagon raises circulating glucose through GCGR-dependent signalling, while GLP-1 supports glucose-dependent insulin secretion; together, proglucagon-derived peptides are central to glucose, appetite and gastrointestinal physiology.
GCG is a core target in metabolic and endocrine research, including pancreatic alpha-cell biology, glucose homeostasis, incretin signalling, diabetes, appetite regulation and gut hormone physiology. Because different tissues process proglucagon into different mature peptides, researchers should confirm which molecular form, species and application are relevant to their experiment when selecting an ABMIUM research product.
Names used across publications, databases and supplier catalogues.
