ABMIUM target intelligence

CD8A

CD8 subunit alpha

CD8 subunit alpha (CD8A), also known as CD8 alpha and T-cell surface glycoprotein CD8 alpha chain, is a T-cell coreceptor protein. This guide connects human NCBI Gene 925, UniProtKB P01732 and ABMIUM catalogue products associated with CD8A.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene925 UniProtP01732

ABMIUM research catalogue

Research Products

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Research context & evidence

About CD8A

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

CD8 alpha is a cell-surface glycoprotein expressed on many cytotoxic T lymphocytes and functions as a coreceptor with the T-cell receptor during recognition of antigen presented by MHC class I molecules. CD8A can form alpha-alpha homodimers or alpha-beta heterodimers with CD8B.

Experimental context

Research context

CD8A / CD8 alpha is commonly studied in cytotoxic T-cell biology, T-cell phenotyping, antigen recognition, MHC class I responses and immune-oncology research. Use the catalogue filters below to compare ABMIUM CD8A research products and confirm species, assay format, application and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

T-cell surface glycoprotein CD8 alpha chainCD8CD8alphaIMD116Leu2MALp32Ly-2Ly-35Ly-BLyt-2