ABMIUM target intelligence
betacellulin
BTC (betacellulin) encodes probetacellulin, an EGF-family membrane precursor that can be proteolytically processed to soluble betacellulin. It is studied as an ERBB-family growth-factor ligand in cell proliferation and differentiation signalling.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Probetacellulin is a single-pass membrane precursor whose processed betacellulin growth factor binds EGFR, ERBB4 and other EGF-receptor family members. Reviewed human evidence supports mitogenic activity, including effects on retinal pigment epithelial and vascular smooth-muscle cells.
BTC is studied in EGF/ERBB receptor signalling, growth-factor processing, epithelial and vascular cell responses, proliferation and differentiation. Abmium products linked below should be selected by checking species, sample type, assay format, application and product-level validation.
Names used across publications, databases and supplier catalogues.
