ABMIUM target intelligence

APOA4

apolipoprotein A4

APOA4 encodes apolipoprotein A4; the mature protein apolipoprotein A-IV (ApoA-IV) is produced predominantly in the intestine and secreted in association with chylomicron particles.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene337 UniProtP06727

ABMIUM research catalogue

Research Products

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Research context & evidence

About APOA4

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

NCBI describes apolipoprotein A-IV as an intestine-derived secreted apolipoprotein associated with chylomicrons and a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. Its precise physiological function is not fully defined.

Experimental context

Research context

APOA4 is studied in intestinal lipid absorption and transport, chylomicron biology, HDL-related lipid metabolism and LCAT regulation. Interpret findings according to sample type, lipoprotein context, species and product-specific validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Apolipoprotein A-IVApo-AIVApoA-IVADTKD6