ABMIUM target intelligence

ANXA5

annexin A5

Annexin A5 (ANXA5), widely known as annexin V, is a calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine and established anticoagulant properties.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene308 UniProtP08758

ABMIUM research catalogue

Research Products

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Research context & evidence

About ANXA5

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Reviewed UniProt P08758 describes ANXA5 as a calcium-dependent phospholipid-binding protein and indirect inhibitor of the thromboplastin-specific coagulation complex. Its phosphatidylserine-binding behaviour underpins widespread experimental use in membrane asymmetry and cell-death research.

Experimental context

Research context

ANXA5/annexin V is studied in phosphatidylserine exposure, membrane asymmetry, coagulation biology and experimental analysis of apoptosis and other cell-death states. Confirm assay format, species, sample type and product-specific validation for the selected ABMIUM reagent.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Annexin VAnnexin A5Annexin-5ANX5CPB-IENX2HEL-S-7PP4RPRGL3VAC-alphQnpA-14191Anchorin CIICalphobindin IEndonexin II