ABMIUM target intelligence
agrin
Agrin (AGRN) is an extracellular matrix and synaptic organizer with a central role in neuromuscular junction formation and maintenance. This ABMIUM record links human AGRN (NCBI Gene 375790; reviewed UniProt O00468) to catalogue-backed research products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Agrin (AGRN) is a heparan-sulfate basal-lamina glycoprotein whose neuronal isoforms organize postsynaptic differentiation at the neuromuscular junction. Reviewed UniProt evidence describes AGRN-LRP4 complex formation, activation of MUSK and clustering of acetylcholine receptors, with additional isoform-dependent roles in neurite outgrowth and synapse biology.
AGRN/agrin is studied in neuromuscular-junction development and maintenance, synapse organization, extracellular-matrix biology, postsynaptic differentiation and acetylcholine-receptor clustering. Confirm species, sample type, application, assay format and product-level validation before selecting an ABMIUM reagent.
Names used across publications, databases and supplier catalogues.
