ABMIUM target intelligence
actinin alpha 2
Actinin alpha 2 (ACTN2), encoding alpha-actinin-2, is a muscle-specific actin-binding protein enriched in skeletal and cardiac muscle. This record connects NCBI Gene 88, UniProtKB P35609 and related ABMIUM catalogue products.
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Research context & evidence
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Alpha-actinin-2, encoded by ACTN2 (actinin alpha 2), is an actin-binding and cross-linking protein of the muscle cytoskeleton. In skeletal and cardiac muscle it localises to the Z-disc, where alpha-actinins help anchor myofibrillar actin filaments and organise the contractile apparatus.
ACTN2 research is relevant to sarcomere and Z-disc organisation, skeletal- and cardiac-muscle structure, cytoskeletal mechanics and muscle-disease models. ABMIUM catalogue products associated with ACTN2 can support target-focused studies; confirm species, sample type, application and product-level validation individually.
Names used across publications, databases and supplier catalogues.
