ABMIUM target intelligence
actin beta
Actin beta (ACTB) encodes actin, cytoplasmic 1, commonly called beta-actin or β-actin, a widely expressed non-muscle cytoskeletal actin. Human ACTB maps to NCBI Gene 60 and reviewed UniProtKB P60709; this target record links the verified target to related ABMIUM catalogue products.
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Research context & evidence
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ACTB is a highly conserved actin that polymerises from monomeric G-actin into F-actin filaments and cross-linked cytoskeletal networks. NCBI and reviewed UniProt describe roles in cell structure, motility and contraction; nuclear G- and F-actin also contribute to transcriptional regulation and repair of damaged DNA.
ACTB/beta-actin is studied in cytoskeletal organisation, cell morphology, adhesion, motility and contractile processes. It is also frequently measured as a reference protein, but suitability as a normalisation control should be validated for each experimental system rather than assumed. Select related ABMIUM research products only after confirming species, sample type, assay/application and product-level validation.
Names used across publications, databases and supplier catalogues.
