ABMIUM target intelligence

IL1RN

interleukin 1 receptor antagonist

IL1RN identifies interleukin 1 receptor antagonist in Homo sapiens (Human). This target record connects NCBI Gene 3557, UniProtKB P18510 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene3557 UniProtP18510

ABMIUM research catalogue

Research Products

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Research context & evidence

About IL1RN

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

IL1RN is an anti-inflammatory interleukin-1 receptor antagonist that counteracts IL1A- and IL1B-driven signalling and helps limit excessive inflammatory responses.

Experimental context

Research context

IL1RN is studied in regulation of IL-1 signalling, innate inflammation, immune homeostasis and disease models involving dysregulated interleukin-1 activity.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Interleukin-1 receptor antagonist proteinIL-1raCRMO2DIRAICIL-1RAIL-1ra3IL1F3IRAPMVCD4F630041P17Rik