ABMIUM target intelligence
arylsulfatase A
ARSA encodes arylsulfatase A, also known as ASA, a lysosomal sulfatase that degrades cerebroside-3-sulfate (sulfatide). The enzyme is a key component of lysosomal glycosphingolipid catabolism. Abmium catalogue products linked below support research into ARSA expression, lysosomal function and sulfatide metabolism.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Arylsulfatase A is a lysosomal hydrolase that catalyses cleavage of sulfate from cerebroside-3-sulfate, producing cerebroside and sulfate; the reaction requires saposin B. This activity supports turnover of sulfatides and normal lysosomal lipid metabolism. Reduced ARSA activity causes sulfatide accumulation, making the enzyme a central mechanistic target in metachromatic leukodystrophy research.
ARSA is studied in lysosomal biology, glycosphingolipid and sulfatide catabolism, myelin-related lipid metabolism and models of arylsulfatase A deficiency. Experimental interpretation should distinguish protein abundance from catalytic activity and lysosomal function. Review the linked Abmium products for species, application, sample type and product-level validation before use.
Names used across publications, databases and supplier catalogues.
