ABMIUM target intelligence
ADAM metallopeptidase domain 12
ADAM metallopeptidase domain 12 (ADAM12), also known as meltrin-alpha/MLTN, is a disintegrin and metalloprotease-family protein with membrane-bound and secreted isoforms. This ABMIUM record links verified ADAM12 biology with catalogue-backed research products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ADAM12 is a zinc-dependent metalloprotease/disintegrin associated with cell adhesion and proteolysis. Reviewed UniProt annotation supports roles in skeletal-muscle regeneration and cell fusion and, by similarity, formation of osteoclasts and macrophage-derived giant cells.
ADAM metallopeptidase domain 12 (ADAM12/meltrin-alpha) is studied in muscle-development and regeneration, cell-fusion, extracellular-remodelling and cell-matrix interaction research. Use the ABMIUM catalogue products on this page to compare ADAM12 reagents and verify species, application and product-level validation.
Names used across publications, databases and supplier catalogues.
