ABMIUM target intelligence
angiotensin II receptor type 1
Angiotensin II receptor type 1 (AGTR1), commonly called the AT1 receptor or AT1R, is a G protein-coupled receptor for angiotensin II and a central signalling component of the renin-angiotensin system. This ABMIUM record links human AGTR1 (NCBI Gene 185; UniProt P30556) to catalogue-backed research products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
AGTR1 encodes the type-1 angiotensin II receptor, a G protein-coupled receptor activated by angiotensin II. Curated UniProt evidence describes coupling to Gq-family G proteins, phospholipase C activation and increased cytosolic calcium, supporting angiotensin-II responses involved in vascular tone, blood-pressure regulation and renal sodium handling.
AGTR1/AT1R is studied in renin-angiotensin signalling, vascular and cardiovascular biology, renal physiology, receptor signalling and calcium-dependent cellular responses. Confirm species, sample type, application, assay format and product-level validation before selecting an ABMIUM reagent.
Names used across publications, databases and supplier catalogues.
