ABMIUM target intelligence
acyl-CoA synthetase long chain family member 4
Acyl-CoA synthetase long chain family member 4 (ACSL4), also known as FACL4 and long-chain-fatty-acid--CoA ligase 4, activates long-chain fatty acids to acyl-CoA esters. Human ACSL4 maps to NCBI Gene 2182 and reviewed UniProtKB O60488; this record links the verified target to related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ACSL4 catalyses activation of long-chain fatty acids to fatty acyl-CoA esters for cellular lipid synthesis and fatty-acid degradation. NCBI and reviewed UniProt describe a preference for arachidonate; UniProt also identifies ACSL4 as a ferroptosis activator by generating activated polyunsaturated-fatty-acid substrates that can undergo lipid peroxidation.
ACSL4 is studied in long-chain fatty-acid metabolism, membrane-lipid composition, arachidonic-acid biology, lipid peroxidation and ferroptosis. Its established names include ACSL4, FACL4 and long-chain acyl-CoA synthetase 4. Select related ABMIUM research products only after confirming species, sample type, assay/application and product-level validation.
Names used across publications, databases and supplier catalogues.
