ABMIUM target intelligence

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

ABL1 is ABL proto-oncogene 1, non-receptor tyrosine kinase, encoding the c-Abl/tyrosine-protein kinase ABL1 protein. This record links the verified human identity (NCBI Gene 25; UniProt P00519) to ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene25 UniProtP00519

ABMIUM research catalogue

Research Products

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Research context & evidence

About ABL1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

ABL1 encodes tyrosine-protein kinase ABL1 (c-Abl), a non-receptor tyrosine kinase involved in cell division, adhesion, differentiation and cellular stress responses. ABL1 is also a recurrent fusion partner in cancer biology, most notably in the BCR::ABL1 fusion context.

Experimental context

Research context

ABL1/c-Abl is widely studied in tyrosine-kinase signalling, cytoskeletal and adhesion responses, cellular stress pathways and oncogenic fusion biology. Use the ABMIUM catalogue products associated with this target to investigate ABL1 protein biology, then confirm species, assay format, application and product-level validation before reagent selection.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Tyrosine-protein kinase ABL1ABLBCR-ABLCHDSKMJTK7c-ABLc-ABL1p150v-abl