ABMIUM target intelligence
signal transducer and activator of transcription 3
STAT3 identifies signal transducer and activator of transcription 3 in Homo sapiens (Human). This target record connects NCBI Gene 6774, UniProtKB P40763 and related ABMIUM catalogue products.
Read full target overviewABMIUM research catalogue
Loading products for STAT3…
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
STAT3 is a signal transducer and transcription factor activated downstream of multiple cytokine and growth-factor receptors. Following phosphorylation and dimerisation, STAT3 can translocate to the nucleus and regulate gene expression controlling processes including proliferation, survival, differentiation and immune responses.
STAT3 is widely studied in cytokine and growth-factor signalling, immunity, inflammation, cell survival, differentiation and cancer models. Reagent selection should consider activation or phosphorylation state, species, sample type, assay format, application and supporting validation.
Names used across publications, databases and supplier catalogues.
