ABMIUM target intelligence
bone morphogenetic protein 6
Bone morphogenetic protein 6 (BMP6/BMP-6) is a secreted TGF-beta-superfamily growth factor involved in developmental, skeletal and iron-homeostasis signalling. ABMIUM catalogue products linked below support research on BMP6 biology.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
BMP6 is a TGF-beta-superfamily ligand that promotes cartilage and bone formation and initiates canonical BMP signalling through receptor complexes including ACVR1 and ACVR2B, activating SMAD1/5/8. Reviewed UniProt also establishes an important role in HAMP/hepcidin regulation and systemic iron metabolism, including signalling linked to hemojuvelin (HJV).
BMP6/BMP-6 is studied in bone and cartilage development, osteogenic differentiation, BMP/SMAD signalling, hepcidin regulation and iron-homeostasis models. Use the catalogue links below to review ABMIUM products associated with BMP6 and confirm product-level validation for the intended species and assay.
Names used across publications, databases and supplier catalogues.
