ABMIUM target intelligence
apolipoprotein C3
APOC3 (apolipoprotein C3) encodes apolipoprotein C-III (ApoC-III), a component of triglyceride-rich lipoproteins including VLDL and chylomicrons and also of HDL. APOC3 is a key regulator of triglyceride homeostasis through effects on lipoprotein production, lipolysis and remnant clearance.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
Apolipoprotein C-III regulates triglyceride-rich lipoprotein metabolism at several steps. NCBI and reviewed UniProt describe APOC3 as promoting hepatic VLDL1 assembly and secretion, inhibiting lipoprotein lipase-mediated triglyceride hydrolysis, and delaying hepatic clearance of triglyceride-rich lipoprotein remnants.
APOC3 is studied in triglyceride homeostasis, VLDL and chylomicron metabolism, lipoprotein lipase regulation and remnant-particle clearance. Interpret measurements in relation to lipoprotein class, fasting and metabolic state, sample type, species and product-specific validation.
Names used across publications, databases and supplier catalogues.
