ABMIUM target intelligence
adhesion G protein-coupled receptor E5
Adhesion G protein-coupled receptor E5 (ADGRE5), widely known as CD97, is an adhesion GPCR expressed prominently in immune-cell contexts. The human ADGRE5 target links NCBI Gene 976 and reviewed UniProtKB P48960 to ABMIUM catalogue reagents for research use.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ADGRE5/CD97 is an EGF-TM7 family adhesion G protein-coupled receptor. The receptor undergoes autoproteolytic processing into a large extracellular subunit and a seven-transmembrane subunit that remain associated at the cell surface. Curated NCBI and UniProt records support roles in cell adhesion and signalling, particularly during leukocyte activation and migration; extracellular EGF-like repeats participate in binding partners including CD55 and chondroitin sulfate.
ADGRE5/CD97 is studied in leukocyte adhesion, recruitment, activation and migration, and more broadly in adhesion-GPCR signalling and immune-cell interactions. When selecting an ABMIUM reagent, match species, assay format, sample type and application to the individual product validation data rather than inferring suitability from target biology alone.
Names used across publications, databases and supplier catalogues.
