ABM-19157
CollaboratorElabscience
Target
Activin Receptor 2B/ACVR2BPurity
>94% by SDS-PAGEMol. weight
14.8 kDaActivity
1. Immobilized human ACVR2B at 10 μg/mL (100 μl/well) can...Species
Mouse
1. Immobilized human ACVR2B at 10 μg/mL (100 μl/well) can bind biotinylated mouse INHBA-HisThe EC50 of biotinylated mouse INHBA-His is 0.161 μg/mL. 2. Immobilized mouse INHBA-his at 10 μg/mL (100 μl/well) can bind human Follistatin ProteinThe EC50 of human Follistatin Protein is 0.39 μg/mL. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 µg/mL in the presence of 10 ng/mL recombinant Activin A.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.