CBY1 Kaninchen-pAk von ELK Biotechnology Read more ›
CBY1 rabbit pAb is a research-use antibody from ELK Biotechnology for studying CBY1 in WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
| Specificity | This antibody detects endogenous levels of CBY1 at Human/Mouse/Rat |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night |
| Collaborator | ELK Biotechnology |
| Partner model | ES17816 |
| Target | CBY1 |
| Research areas | >>Wnt signaling pathway |
| Reactivity | Mensch; Maus; Ratte |
| Applications | WB |
| Conjugation | Unkonjugiert |
| Dilution range | WB 1:500-2000 |
| Host | Kaninchen |
| Clonality | Polyklonal |
| Isotype | IgG |
| Immunogen | Synthetisiertes Peptid, das von menschlichem CBY1 (AS-Bereich: 71-121) abgeleitet ist |
| Concentration | 1 mg/ml |
| Purification | Der Antikörper wurde durch Affinitätschromatographie mittels spezifischem Immunogen aus Kaninchenserum affinitätsgereinigt. |
| Assay type | Antikörpervalidierung/-anwendung |
| Expression system | Weit verbreitet exprimiert. Höhere Expression in Herz, Skelettmuskel, Niere und Plazenta. Auch in Gehirn, Lunge, Leber und Hoden gefunden. Deutlich herunterreguliert in Schilddrüsen- und metastasierten Gebärmuttertumoren. |
| Purity | Der Antikörper wurde durch Affinitätschromatographie mittels spezifischem Immunogen aus Kaninchenserum affinitätsgereinigt. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
| Species | Dilution | Notes |
|---|---|---|
| Mensch | WB 1:500-2000 | — |
| Maus | — | — |
| Ratte | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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