GTR2 rabbit pAb
GTR2-Kaninchen-pAk von ELK Biotechnology Read more ›
Product Description
GTR2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving GTR2.
Background
This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Additional antibody information
| Specificity | GTR2 Polyclonal Antibody detects endogenous levels of protein. |
|---|---|
| Validation evidence captions | Western Blot analysis of varius cell lysis. Primary Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS23920 was diluted at 1:10000 |
Key Facts
| Target | GTR2 |
| Concentration | 1 mg/ml |
| Working concentration | WB 1:500-2000 ELISA 1:5000-20000 |
| Species reactivity | Mensch;Ratte;Maus; |
| Observed band | 57 kD |
| Cellular localization | Zellmembran; Multi-Pass-Membranprotein. |
| Purity | Der Antikörper wurde mittels Affinitätschromatographie unter Verwendung eines Epitop-spezifischen Immunogens aus Kaninchenantiserum affinitätsgereinigt. |
| Form / buffer | Flüssigkeit in PBS, die 50 % Glycerin und 0,02 % Natriumazid enthält. |
| Research area | >>Insulinsekretion;>>Prolaktin-Signalweg;>>Glucagon-Signalweg;>>Typ-II-Diabetes mellitus;>>Insulinresistenz;>>MODY (Maturity-Onset Diabetes of the Young);>>Kohlenhydratverdauung und -absorption;>>Zentraler Kohlenstoffmetabolismus bei Krebs |
| Host species | Kaninchen |
| Clonality | Polyklonal |
| Isotype | IgG |
| Conjugation | Unkonjugiert |
| Tested applications |
WBELISA |
| Dilution range | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthetisches Peptid, das von menschlichem Protein abgeleitet ist. AA-Bereich: 220-300 |
| Purification | Der Antikörper wurde mittels Affinitätschromatographie unter Verwendung eines Epitop-spezifischen Immunogens aus Kaninchenantiserum affinitätsgereinigt. |
Reactivity & Application Validation
3 artens| Arten | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Ratte | |||||||
| Maus |
| Arten | Dilution | Notes |
|---|---|---|
| Mensch | WB 1:500-2000 ELISA 1:5000-20000 | — |
| Ratte | — | — |
| Maus | — | — |
| Arten | Dilution | Notes |
|---|
Spezifikationen
Lagerung und Stabilität
Compliance & Zertifizierungen
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.