Kininogen 1 Kaninchen-pAk von ELK Biotechnology Read more ›
Kininogen 1 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying Kininogen 1 in WB, IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Kininogens are inhibitors of thiol proteases; HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL1 is abundantly expressed in neuronal tissues and testes.
| Validation evidence captions | Western blot analysis of 1) Human Serum, 2) Rat Kidney Tissue Lysate , 3) Mouse Kidney Tissue Lysate using (EA367)Rabbit pAb diluted at 1:1000. |
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| Collaborator | ELK Biotechnology |
| Partner model | EA367 |
| Target | Kininogen 1 |
| Research areas | Antibody Research |
| Reactivity | Mensch, Maus, Ratte |
| Applications | WB,IHC |
| Conjugation | Unkonjugiert |
| Dilution range | WB 1:1500-1.000 IHC 1:100-200 |
| Host | Kaninchen |
| Clonality | Polyklonal |
| Isotype | IgG |
| Immunogen | Rekombinantes Protein |
| Concentration | 1 mg/ml |
| Assay type | Antikörpervalidierung/-anwendung |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
| Species | Dilution | Notes |
|---|---|---|
| Mensch | WB 1:1500-1 | — |
| Maus | — | — |
| Ratte | — | — |
| Species | Dilution | Notes |
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Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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