Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM92365

Kininogen 1 Rabbit pAb

ISO 9001|ABMIUM Verified™|Antikörper

Kininogen 1 Kaninchen-pAk von ELK Biotechnology Read more ›

Kininogen 1 Rabbit pAb
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Kininogen 1 Rabbit pAb

Product Description

Kininogen 1 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying Kininogen 1 in WB, IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Kininogens are inhibitors of thiol proteases; HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL1 is abundantly expressed in neuronal tissues and testes.

Additional antibody information

Validation evidence captions Western blot analysis of 1) Human Serum, 2) Rat Kidney Tissue Lysate , 3) Mouse Kidney Tissue Lysate using (EA367)Rabbit pAb diluted at 1:1000.

Key Facts

Product typePrimary Antibody Target: Kininogen 1
Collaborator ELK Biotechnology
Partner model EA367
Target Kininogen 1
Research areasAntibody Research
Reactivity Mensch, Maus, Ratte
Applications WB,IHC
ConjugationUnkonjugiert
Dilution rangeWB 1:1500-1.000 IHC 1:100-200
Host Kaninchen
Clonality Polyklonal
Isotype IgG
Immunogen Rekombinantes Protein
Concentration 1 mg/ml
Assay type Antikörpervalidierung/-anwendung
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Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Erwartete Leistung Nicht geeignet
SpeciesWBIHCIFELISAIPFCMChIP
Mensch
Maus
Ratte
ABMIUM Validated™ WB
Species Dilution Notes
Mensch WB 1:1500-1
Maus
Ratte
ABMIUM Validated™ IHC
Species Dilution Notes

Spezifikationen

Target
Kininogen 1
Also known as
BDK, Fitzgerald-Faktor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysylbradykinin, Kininogen 1, KNG, KNG1
Concentration
1 mg/ml
Working concentration
WB 1:1500-1.000 IHC 1:100-200
Form / buffer
Antikörperlösung
Host species
Kaninchen
Clonality
Polyklonal
Isotype
IgG
Conjugation
Unkonjugiert
Species reactivity
Mensch, Maus, Ratte
Tested applications
WBIHC
Immunogen
Rekombinantes Protein
Observed band
45-120 kDa
Cellular localization
Abgesondert
Dilution range
WB 1:1500-1.000 IHC 1:100-200

Lagerung und Stabilität

Vermeiden Sie wiederholte Frost-Tau-Zyklen.
Long-term storage
PBS mit 0,02 % Natriumazid und 50 % Glycerin pH 7,4. Bei -20°C lagern. Wiederholtes Einfrieren und Auftauen vermeiden.
Storage conditions
PBS mit 0,02 % Natriumazid und 50 % Glycerin pH 7,4. Bei -20 °C lagern. Wiederholtes Einfrieren und Auftauen vermeiden.

Compliance & Zertifizierungen

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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