ATG4c Rabbit pAb von ELK Biotechnology Read more ›
ATG4c Rabbit pAb is a research-use antibody from ELK Biotechnology for studying ATG4c in IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG4c（EA349）Rabbit pAb diluted at 1:200 | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG4c （EA349）Rabbit pAb diluted at 1:200 |
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| Collaborator | ELK Biotechnology |
| Partner model | EA349 |
| Target | ATG4c |
| Research areas | Antibody Research |
| Reactivity | Mensch, Maus, Ratte |
| Applications | IHC |
| Conjugation | Unkonjugiert |
| Dilution range | IHC 1:100-200 |
| Host | Kaninchen |
| Clonality | Polyklonal |
| Isotype | IgG |
| Immunogen | Rekombinantes Protein |
| Concentration | 1 mg/ml |
| Assay type | Antikörpervalidierung/-anwendung |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
| Species | Dilution | Notes |
|---|---|---|
| Mensch | IHC 1:100-200 | — |
| Maus | — | — |
| Ratte | — | — |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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