ATG4a Rabbit pAb
ATG4a Kaninchen pAk von ELK Biotechnology Read more ›
Product Description
ATG4a Rabbit pAb is an ELK Biotechnology antibody for research workflows involving ATG4a.
Background
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).
Additional antibody information
| Validation evidence captions | Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG4a （EA347）Rabbit pAb diluted at 1:200 | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG4a （EA347）Rabbit pAb diluted at 1:200 |
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Key Facts
| Target | ATG4a |
| Also known as | Apg4a, Atg4al, Autl2, Cysteinprotease ATG4A-Antikörper |
| Concentration | 1 mg/mL |
| Working concentration | IHC 1:100-200 |
| Species reactivity | Mensch, Maus, Ratte |
| Observed band | 45 kDa |
| Cellular localization | Zytoplasma |
| Form / buffer | Antikörperlösung |
| Research area | Antikörperforschung |
| Host species | Kaninchen |
| Clonality | Polyklonal |
| Isotype | IgG |
| Conjugation | Unkonjugiert |
| Tested applications |
IHC |
| Dilution range | IHC 1:100-200 |
| Immunogen | Rekombinantes Protein |
Reactivity & Application Validation
3 artens| Arten | WB | IHC | IF | ELISA | IP | FCM | CHIP |
|---|---|---|---|---|---|---|---|
| Mensch | |||||||
| Maus | |||||||
| Ratte |
| Arten | Dilution | Notes |
|---|---|---|
| Mensch | IHC 1:100-200 | — |
| Maus | — | — |
| Ratte | — | — |
Spezifikationen
Lagerung und Stabilität
Compliance & Zertifizierungen
Manufactured under ISO 9001:2015 quality management standards.
Not intended for diagnostic or therapeutic use.