Anticorps polyclonal anti-SAP18 de lapin de la société ELK Biotechnology Read more ›
SAP18 rabbit pAb is a research-use antibody from ELK Biotechnology for studying SAP18 in WB, IHC workflows with listed reactivity for Human, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008],
| Specificity | This antibody detects endogenous levels of SAP18 at Human/Mouse |
|---|---|
| Validation evidence captions | Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night | Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min). |
| Collaborator | ELK Biotechnology |
| Partner model | ES13202 |
| Target | SAP18 |
| Research areas | >>Nucleocytoplasmic transport, >>mRNA surveillance pathway |
| Reactivity | Humain ; Souris |
| Applications | WB,IHC |
| Conjugation | Non conjugué |
| Dilution range | WB 1:500-2000; IHC-p 1:50-300 |
| Host | Lapin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Peptide synthétisé dérivé de la SAP18 humaine |
| Concentration | 1 mg/ml |
| Purification | L'anticorps a été purifié par affinité à partir de sérum de lapin par chromatographie d'affinité en utilisant un immunogène spécifique. |
| Assay type | Validation/application des anticorps |
| Expression system | Omniprésent. |
| Purity | L'anticorps a été purifié par affinité à partir de sérum de lapin par chromatographie d'affinité en utilisant un immunogène spécifique. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Souris |
| Species | Dilution | Notes |
|---|---|---|
| Humain | WB 1:500-2000;IHC-p 1:50-300 | — |
| Souris | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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