pAb de lapin Gab 1 (phospho Tyr627) de ELK Biotechnology Read more ›
Gab 1 (phospho Tyr627) rabbit pAb is a research-use antibody from ELK Biotechnology for studying Gab 1 in WB, ELISA workflows with listed reactivity for Human, Mouse, Monkey. Specifications and supporting documents below should be reviewed when planning the experiment.
GRB2 associated binding protein 1(GAB1) Homo sapiens The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
| Specificity | Phospho-Gab 1 (Y627) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y627. |
|---|---|
| Validation evidence captions | Western Blot analysis of various cells using Phospho-Gab 1 (Y627) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using GAB1 (Phospho-Tyr627) Antibody | Western blot analysis of GAB1 (Phospho-Tyr627) Antibody. The lane on the right is blocked with the GAB1 (Phospho-Tyr627) peptide. |
| Collaborator | ELK Biotechnology |
| Partner model | ES1318 |
| Target | Gab 1 |
| Research areas | >>EGFR tyrosine kinase inhibitor resistance, >>ErbB signaling pathway, >>Ras signaling pathway, >>Phospholipase D signaling pathway, >>Neurotrophin signaling pathway, >>Bacterial invasion of epithelial cells, >>Proteoglycans in cancer, >>Renal cell carcinoma, >>Hepatocellular carcinoma, >>Gastric cancer |
| Reactivity | Humain;Souris;Singe |
| Applications | WB,ELISA |
| Conjugation | Non conjugué |
| Dilution range | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Non encore testé dans d'autres applications. |
| Host | Lapin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | L'antisérum a été produit contre un peptide synthétisé dérivé de la GAB1 humaine autour du site de phosphorylation Tyr627 Gamme d'AA: 611-643 |
| Concentration | 1 mg/ml |
| Purification | L'anticorps a été purifié par affinité à partir de l'antisérum de lapin par chromatographie d'affinité utilisant un immunogène spécifique de l'épitope. |
| Assay type | Validation/application des anticorps |
| Expression system | Testicule,Embryon entier, |
| Purity | L'anticorps a été purifié par affinité à partir de l'antisérum de lapin par chromatographie d'affinité utilisant un immunogène spécifique de l'épitope. |
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Souris | |||||||
| Singe |
| Species | Dilution | Notes |
|---|---|---|
| Humain | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Pas encore testé pour d'autres applications. | — |
| Souris | — | — |
| Singe | — | — |
| Species | Dilution | Notes |
|---|
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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