Recombinant Human IRF5 (C-6His) from ELK Biotechnology Read more ›
Recombinant Human IRF5 (C-6His) is a research-use recombinant protein from ELK Biotechnology preparation representing IRF5 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.
Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.
| Delivery condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
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| Collaborator | ELK Biotechnology |
| Partner model | EPT255 |
| Target | IRF5 |
| Research areas | Molecular Biology |
| Reactivity | Product QC:C |
| Applications | Protein research |
| Assay type | Recombinant protein |
| Purity | >95% by SDS-PAGE |
| Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Category | Purity | Endotoxin | Bioactivity |
|---|---|---|---|
| Product QC |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
Quality management certification.
For research applications. Not for diagnostic use.
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