Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM92555

Caspase-3 (4B8) Mouse mAb

ISO 9001|ABMIUM Verified™|Antibody

Caspase-3 (4B8) Mouse mAb from ELK Biotechnology Read more ›

Caspase-3 (4B8) Mouse mAb
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Caspase-3 (4B8) Mouse mAb

Product Description

Caspase-3 (4B8) Mouse mAb is a research-use antibody from ELK Biotechnology for studying Caspase-3 (4B8) in IHC workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP).

Additional antibody information

Validation evidence captions Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Caspase-3(EM1266)Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using Caspase-3(EM1266)Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Mouse LiverTissue using Caspase-3(EM1266)Mouse mAb diluted at 1:200.

Key Facts

Product typePrimary Antibody Target: Caspase-3 (4B8)
Collaborator ELK Biotechnology
Partner model EM1266
Target Caspase-3 (4B8)
Research areasAntibody Research
Reactivity Human,Rat,Mouse
Applications IHC
ConjugationUnconjugated
Dilution rangeIHC 1:100-200
Host Mouse
Clonality Monoclonal
Isotype IgG1
Immunogen Synthetic Peptide
Concentration 1mg/mL
Assay type Antibody validation/application
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Application Validation Matrix

3 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Rat
Mouse
ABMIUM Validated™ IHC
Species Dilution Notes
Human IHC 1:100-200
Rat
Mouse

Specifications

Target
Caspase-3 (4B8)
Also known as
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody
Concentration
1mg/mL
Working concentration
IHC 1:100-200
Form / buffer
Liquid
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Species reactivity
Human,Rat,Mouse
Tested applications
IHC
Immunogen
Synthetic Peptide
Observed band
17,32kDa
Cellular localization
Cytoplasm
Dilution range
IHC 1:100-200

Storage & Stability

Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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