Collaborator ELK Biotechnology
Primary AntibodyISO 9001:2015
ABM94666

ROM1 rabbit pAb

ISO 9001|ABMIUM Verified™|Antibody

ROM1 rabbit pAb from ELK Biotechnology Read more ›

ROM1 rabbit pAb
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ROM1 rabbit pAb

Product Description

ROM1 rabbit pAb is a research-use antibody from ELK Biotechnology for studying ROM1 in WB workflows with listed reactivity for Human, Mouse, Rat, C. parvum. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008],

Additional antibody information

Specificity This antibody detects endogenous levels of ROM1 at Human/Mouse/Rat
Validation evidence captions Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night

Key Facts

Product typePrimary Antibody Target: ROM1
Collaborator ELK Biotechnology
Partner model ES13355
Target ROM1
Research areasAntibody Research
Reactivity Human,Mouse,Rat,C. parvum
Applications WB
ConjugationUnconjugated
Dilution rangeWB 1:500-2000
Host Rabbit
Clonality Polyclonal
Isotype IgG
Immunogen Synthesized peptide derived from human ROM1 AA range: 163-213
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Assay type Antibody validation/application
Expression system Retina photoreceptors (at protein level) (PubMed:1610568, PubMed:8504299). In rim region of ROS disks (PubMed:1610568).
Purity The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Application Validation Matrix

4 speciess
ABMIUM Validated™ ABMIUM Verified™ Expected Performance Not suitable
SpeciesWBIHCIFELISAIPFCMChIP
Human
Mouse
Rat
C. parvum
ABMIUM Validated™ WB
Species Dilution Notes
Human WB 1:500-2000
Mouse
Rat
C. parvum

Specifications

Target
ROM1
Concentration
1 mg/ml
Working concentration
WB 1:500-2000
Purity
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form / buffer
Liquid
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Species reactivity
Human,Mouse,Rat,C. parvum
Tested applications
WB
Immunogen
Synthesized peptide derived from human ROM1 AA range: 163-213
Cellular localization
Photoreceptor inner segment membrane ; Multi-pass membrane protein . Photoreceptor outer segment membrane ; Multi-pass membrane protein .
Dilution range
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage & Stability

Long-term storage
'-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Compliance & Certifications

ABMIUM
ABMIUM Verified

Collaborator meets ABMIUM quality standards and overall product performance standards have been met.

ISO
ISO 9001

Quality management certification.

RUO
Research Use Only

For research applications. Not for diagnostic use.

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