Human Complement C5a PicoKine® Quick ELISA Kit

Human Complement C5a PicoKine® Quick ELISA Kit is a research-use ELISA kit from Boster Bio for measuring Complement C5 in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA) samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human Complement C5a PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human Complement C5a in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

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