ABMIUM target intelligence

KDR

kinase insert domain receptor

KDR identifies kinase insert domain receptor in Homo sapiens (Human). This target record connects NCBI Gene 3791, UniProtKB P35968 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene3791 UniProtP35968

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Vascular endothelial growth factor receptor 2VEGFR-2FLK1CD309VEGFRVGFR26130401C07Krd-1Ly73orvsVEGFR-2

Biological function

KDR (VEGFR2/CD309) is a receptor tyrosine kinase for VEGF-family ligands including VEGFA. It is a major mediator of endothelial-cell proliferation, survival, migration and differentiation and has central roles in angiogenesis and vascular development.

Research context

KDR is widely studied in angiogenesis, endothelial signalling, vascular development, permeability and tumour vascular biology. Reagent selection should consider species, endothelial context, sample type, assay format, application and supporting validation.