{"product_id":"human-pcsk9-proprotein-convertase-9-elisa-kit-picokine-ek1147","title":"Human PCSK9\/Proprotein Convertase 9 ELISA Kit PicoKine®","description":"\u003cp\u003eHuman PCSK9\/Proprotein Convertase 9 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Proprotein convertase subtilisin\/kexin type 9 in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.\u003c\/p\u003e\nHuman PCSK9\/Proprotein Convertase 9 ELISA Kit PicoKine® (96 Tests). Quantitate Human PCSK9 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg\/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.\u003cp\u003eProprotein convertase subtilisin\/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins (LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":56042446291284,"sku":"ABM32789","price":442.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ek1147.png?v=1781655503","url":"https:\/\/www.abmium.com\/zh\/products\/human-pcsk9-proprotein-convertase-9-elisa-kit-picokine-ek1147","provider":"ABMIUM","version":"1.0","type":"link"}