{"product_id":"human-pcsk9-elisa-kit-ez-set-diy-antibody-pairs-ez1147","title":"Human PCSK9 ELISA Kit EZ-Set™ (DIY Antibody Pairs)","description":"\u003cp\u003eHuman PCSK9 ELISA Kit EZ-Set™ (DIY Antibody Pairs) is a research-use antibody from Boster Bio for studying Proprotein convertase subtilisin\/kexin type 9 in ELISA workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\nHuman PCSK9 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human PCSK9 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate).\u003cp\u003eProprotein convertase subtilisin\/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins (LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"5 plates\/kit","offer_id":56042543120724,"sku":"ABM31941","price":443.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ek1147_1.png?v=1781658719","url":"https:\/\/www.abmium.com\/zh\/products\/human-pcsk9-elisa-kit-ez-set-diy-antibody-pairs-ez1147","provider":"ABMIUM","version":"1.0","type":"link"}