{"product_id":"anti-pms2-antibody-picoband-a01028","title":"Anti-PMS2 Antibody Picoband®","description":"\u003cp\u003eAnti-PMS2 Antibody Picoband® is a research-use antibody from Boster Bio for studying Mismatch repair endonuclease PMS2 in ELISA, Flow Cytometry, IHC, IHC-P, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\nBoster Bio Anti-PMS2 Antibody Picoband® catalog # A01028. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.\u003cp\u003eMismatch repair endonuclease PMS2 is an enzyme that in humans is encoded by the PMS2 gene. The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion\/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA (X)2E (X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"Unconjugated \/ 100 μg\/vial","offer_id":56039986856276,"sku":"ABM22227-1","price":328.0,"currency_code":"GBP","in_stock":true},{"title":"Biotin \/ 100 μg\/vial","offer_id":56039986889044,"sku":"ABM22227-2","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Cy3 \/ 100 μg\/vial","offer_id":56039986921812,"sku":"ABM22227-3","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro488 \/ 100 μg\/vial","offer_id":56039986954580,"sku":"ABM22227-4","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro550 \/ 100 μg\/vial","offer_id":56039986987348,"sku":"ABM22227-5","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro594 \/ 100 μg\/vial","offer_id":56039987020116,"sku":"ABM22227-6","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"FITC \/ 100 μg\/vial","offer_id":56039987052884,"sku":"ABM22227-7","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"HRP \/ 100 μg\/vial","offer_id":56039987085652,"sku":"ABM22227-8","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"APC \/ 100 μg\/vial","offer_id":56039987118420,"sku":"ABM22227-9","price":726.0,"currency_code":"GBP","in_stock":true},{"title":"PE \/ 100 μg\/vial","offer_id":56039987151188,"sku":"ABM22227-10","price":726.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro647 \/ 100 μg\/vial","offer_id":56039987183956,"sku":"ABM22227-11","price":593.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/A01028-PMS2-primary-antibodies-WB-testing-1.jpg?v=1781637745","url":"https:\/\/www.abmium.com\/zh\/products\/anti-pms2-antibody-picoband-a01028","provider":"ABMIUM","version":"1.0","type":"link"}