{"product_id":"human-leptin-elisa-kit-ez-set-diy-antibody-pairs-ez0437","title":"Human Leptin ELISA Kit EZ-Set™ (DIY Antibody Pairs)","description":"\u003cp\u003eHuman Leptin ELISA Kit EZ-Set™ (DIY Antibody Pairs) is a research-use antibody from Boster Bio for studying Leptin in ELISA workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\nHuman Leptin ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human LEP in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).\u003cp\u003eLeptin (or obese, OB) is a circulating hormone that is expressed abundantly and specifically in the adipose tissue. Human ob protein is a 166-amino acid polypeptide with a putative signal sequence and is 84 and 83% homologous to the mouse and rat ob proteins, respectively. Northern blot analysis reveals that OB RNA is present at a high level in adipose tissue but at much lower levels in placenta and heart. Indeed, Leptin is first described as an adipocyte-derived signalling factor, which, after interaction with its receptors, induces a complex response including control of bodyweight and energy expenditure. Leptin seems in addition to its role in metabolic control to have important roles in reproduction and neuroendocrine signalling. Leptin is a powerful inhibitor of bone formation in vivo. Comparative mapping of mouse and human DNA indicates that the ob gene is located within a region of mouse chromosome 6 that is homologous to a portion of human chromosome 7q. The standard product used in this kit is recombinant human Leptin.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"5 plates\/kit","offer_id":56042545054036,"sku":"ABM31957","price":443.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EZ0437.png?v=1781658750","url":"https:\/\/www.abmium.com\/tr\/products\/human-leptin-elisa-kit-ez-set-diy-antibody-pairs-ez0437","provider":"ABMIUM","version":"1.0","type":"link"}