{"product_id":"anti-p27kip1-cdkn1b-antibody-monoclonal-dcs-72-ma1076","title":"Anti-p27Kip1 CDKN1B Antibody (Monoclonal, DCS-72)","description":"\u003cp\u003eAnti-p27Kip1 CDKN1B Antibody (Monoclonal, DCS-72) is a research-use antibody from Boster Bio for studying Cyclin-dependent kinase inhibitor 1B in IF\/ICC, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\nBoster Bio Anti-p27Kip1 CDKN1B Antibody (Monoclonal, DCS-72) catalog # MA1076. Tested in ICC, WB applications. This antibody reacts with Human, Mouse, Rat.\u003cp\u003eP27 (kip1), also known as cyclin dependent kinase inhibitor 1B (CDKN1B), is a major target of AFX-like forkhead proteins. CDKN1B (p27) belongs to the Cip\/Kip family and functions as an important cell cycle gatekeeper. Phosphorylation leads to the ubiquitination and degradation of CDKN1B. P27 (kip1) mapped to 12p13. An increase in p27 causes proliferating cells to exit from the cell cycle, and a decrease in p27 is necessary for quiescent cells to resume division. Abnormally low amounts of p27 are associated with pathological states of excessive cell proliferation, especially cancers. Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"Unconjugated \/ 100 μg\/vial","offer_id":56042972643668,"sku":"ABM27083","price":328.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/boster-box_ee774431-9fec-439e-8d50-a79d4880dcb4.png?v=1781661503","url":"https:\/\/www.abmium.com\/tr\/products\/anti-p27kip1-cdkn1b-antibody-monoclonal-dcs-72-ma1076","provider":"ABMIUM","version":"1.0","type":"link"}