{"product_id":"elk-es7643-camkiialpha-delta-rabbit-pab","title":"CaMKIIα\/δ rabbit pAb","description":"\u003cp\u003eCaMKIIα\/δ rabbit pAb is a research-use antibody from ELK Biotechnology for studying CaMK2 in WB, IHC, IF, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe product of this gene belongs to the serine\/threonine protein kinases family, and to the Ca(2+)\/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCaMKIIα\/δ Polyclonal Antibody detects endogenous levels of CaMKIIα\/δ protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of NIH-3T3\/K562 cells using CaMKIIα\/δ Polyclonal Antibody diluted at 1:500 | Immunofluorescence analysis of MCF7 cells, using CaMK2 alpha\/delta Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CaMK2 alpha\/delta Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from NIH\/3T3 and K562 cells, using CaMK2 alpha\/delta Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187299365204,"sku":"ABM109417","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187299397972,"sku":"ABM99553","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7643-c-1.jpg?v=1782051929","url":"https:\/\/www.abmium.com\/sv\/products\/elk-es7643-camkiialpha-delta-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}