{"product_id":"mouse-tpor-mpl-thrombopoietin-r-elisa-kit-picokine-ek1436","title":"Mouse TPOR\/MPL\/Thrombopoietin R ELISA Kit PicoKine®","description":"\u003cp\u003eMouse TPOR\/MPL\/Thrombopoietin R ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Thrombopoietin receptor in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA). samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.\u003c\/p\u003e\nMouse TPOR\/MPL ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Mpl in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg\/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.\u003cp\u003eThe thrombopoietin receptor (TPOR), also known as CD110, is a protein that in humans is encoded by the MPL (myeloproliferative leukemia virus) oncogene. The human MPL gene is mapped to chromosome 1p34. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":56042463396180,"sku":"ABM33081","price":664.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ek1436_1.png?v=1781656214","url":"https:\/\/www.abmium.com\/pt\/products\/mouse-tpor-mpl-thrombopoietin-r-elisa-kit-picokine-ek1436","provider":"ABMIUM","version":"1.0","type":"link"}