{"product_id":"elk-es8546-fam48a-rabbit-pab","title":"FAM48A rabbit pAb","description":"\u003cp\u003eFAM48A rabbit pAb is a research-use antibody from ELK Biotechnology for studying FAM48A in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and\/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eThe antibody detects endogenous FAM48A protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of mouse-kidney cells using Antibody diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187431551316,"sku":"ABM109718","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187431584084,"sku":"ABM99854","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES8546-c-1.jpg?v=1782055062","url":"https:\/\/www.abmium.com\/pt\/products\/elk-es8546-fam48a-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}