{"product_id":"elk-es12474-tyk2-phospho-tyr1054-1055-rabbit-pab","title":"Tyk2 (phospho-Tyr1054\/1055) rabbit pAb","description":"\u003cp\u003eTyk2 (phospho-Tyr1054\/1055) rabbit pAb is a research-use antibody from ELK Biotechnology for studying Tyk2 in WB workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003etyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eThis antibody detects endogenous levels of Human Tyk2 (phospho-Tyr1054 or 1055)\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185124880724,"sku":"ABM103995","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185124913492,"sku":"ABM94131","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/3_d771ad30-f6fd-4570-8623-1b9aad895df4.png?v=1783151207","url":"https:\/\/www.abmium.com\/pt\/products\/elk-es12474-tyk2-phospho-tyr1054-1055-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}