{"product_id":"tribio-vu0134992-kir4-1-blocker","title":"VU0134992, Kir4.1 blocker","description":"\u003cp\u003eBlocker of the inward rectifier potassium channel K ir 4.1 (IC 50 = 970 nM). It also inhibits K ir 3.1\/3.2, K ir 3.1\/3.4, and K ir 4.2 with similar potency. VU0134992 induced diuresis, natriuresis, and kaliuresis in Sprague-Dawley rats suggesting therapeutic blood pressure lowering potential. It reduced polymyxin-induced nephrotoxicity in cell culture and mouse explant kidney tissue\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411076424020,"sku":"ABM148945-1","price":145.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411076456788,"sku":"ABM148945-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4651.png?v=1791105150","url":"https:\/\/www.abmium.com\/products\/tribio-vu0134992-kir4-1-blocker","provider":"ABMIUM","version":"1.0","type":"link"}