{"product_id":"tribio-vgx-1027-immunomodulator-cytokine-release-inhibitor","title":"VGX-1027, Immunomodulator; Cytokine release inhibitor","description":"\u003cp\u003eImmunomodulator. Inhibits secretion of IL-1β, TNF-α, and IL-10 from murine macrophages stimulated with LPS and spares T cell function. Ameliorates the course of acute and chronic immunoinflammatory conditions such as carrageenan-induced pleurisy, LPS-induced lethality and type II collagen-induced arthritis in mouse models. Prevents spontaneous and accelerated forms of autoimmune diabetes in a NOD mouse model. Moldulates genes involved in LPS-induced Toll-like receptor 4 activation in a mouse Lupus model. Displays protective effects in particulate matter-induced acute lung injury by blocking TLR4 signaling\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411090874708,"sku":"ABM148935-1","price":262.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411090907476,"sku":"ABM148935-2","price":74.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI3409.png?v=1791105183","url":"https:\/\/www.abmium.com\/products\/tribio-vgx-1027-immunomodulator-cytokine-release-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}