{"product_id":"tribio-telaprevir-hepatitis-c-protease-inhibitor","title":"Telaprevir, Hepatitis C protease inhibitor","description":"\u003cp\u003eHepatitis C NS3\/4A protease inhibitor that is in clinical use for genotype 1 infections (IC50 = 354 nM genotype 1b replicon cells; IC50 = 280 nM human fetal hepatocytes infected with genotype 1a HCV-positive patient sera). It has been shown to inhibit SARS-CoV2 proteases MPro (IC50 = 15 µM) and 3CLPro (IC50 = 56 µM). Telaprevir is also an allosteric inhibitor of DnaK, the bacterial homolog of Hsp70. It enhanced the efficacy of aminoglycoside antibiotics and reduced resistance to the tuberculosis drug rifampin\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411083403604,"sku":"ABM148823-1","price":245.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57411083436372,"sku":"ABM148823-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4929.png?v=1791105166","url":"https:\/\/www.abmium.com\/products\/tribio-telaprevir-hepatitis-c-protease-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}