{"product_id":"tribio-stavudine-hiv-reverse-transcriptase-inhibitor-nlrp3-inflammasome-inhibitor","title":"Stavudine, HIV reverse transcriptase inhibitor; NLRP3 inflammasome inhibitor","description":"\u003cp\u003eThymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs). Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition. Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"1 G","offer_id":57411088253268,"sku":"ABM148785-1","price":278.0,"currency_code":"GBP","in_stock":true},{"title":"200mg","offer_id":57411088286036,"sku":"ABM148785-2","price":85.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1266.png?v=1791105178","url":"https:\/\/www.abmium.com\/products\/tribio-stavudine-hiv-reverse-transcriptase-inhibitor-nlrp3-inflammasome-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}