{"product_id":"tribio-quizartinib-selective-flt3-inhibitor","title":"Quizartinib, Selective FLT3 inhibitor","description":"\u003cp\u003eQuizartinib is a potent and selective inhibitor of FLT3 (Kd = 1.6nM, IC50 = 0.56 nM MV4-11 cells). It is in clinical trials for treatment of Acute Myelogenous Leukemia (AML). Quizartinib priming resulted in prevention of myelosuppression in mice treated with 5-FU and Gemcitabine. Quizartinib showed significant reversal of ABCG2-mediated multidrug resistance (@ 3 µM) via antagonism of drug efflux function\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57411061154132,"sku":"ABM148629-1","price":256.0,"currency_code":"USD","in_stock":true},{"title":"5 MG","offer_id":57411061186900,"sku":"ABM148629-2","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4813.png?v=1791104982","url":"https:\/\/www.abmium.com\/products\/tribio-quizartinib-selective-flt3-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}