{"product_id":"tribio-ko-143-bcrp-inhibitor","title":"Ko-143, BCRP inhibitor","description":"\u003cp\u003eA potent and selective inhibitor of the breast cancer resistance protein multidrug transporter (BCRP\/ABCG2). Reverses resistance of MTX and topotecan at 25 nM in human and mouse cell lines. Also inhibits ABCB1 and ABCC1 at concentrations \u0026gt;1 μM. Prevents the export of the FAAH inhibitor URB937 from the CNS. Forces prostate stem cells to undergo and AR-modulated differentiation to an androgen deprivation therapy-sensitive luminal phenotype. Active in vivo\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410919727444,"sku":"ABM147239-1","price":736.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410919760212,"sku":"ABM147239-2","price":163.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1074.png?v=1791103639","url":"https:\/\/www.abmium.com\/products\/tribio-ko-143-bcrp-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}