{"product_id":"tribio-iu1-usp-14-inhibitor","title":"IU1, USP-14 inhibitor","description":"\u003cp\u003eSelective inhibitor of Usp14 (IC50\u0026lt;4 μM). Enhances proteasome activity and substrate proteolysis. Inhibits Dengue virus replication. In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load. Attenuates ischemia\/reperfusion-induced neuronal injury in a mouse model. Cell permeable\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410908193108,"sku":"ABM147204-1","price":82.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410908225876,"sku":"ABM147204-2","price":327.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1197-1.png?v=1791103613","url":"https:\/\/www.abmium.com\/products\/tribio-iu1-usp-14-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}