{"product_id":"tribio-icilin-trpm8-channel-activator","title":"Icilin, TRPM8 channel activator","description":"\u003cp\u003eIcilin is an agonist of cold-sensitive TRP channels with 2.5-fold greater efficacy and 200-fold greater potency than menthol (EC50 = 0.36 µM for CRM1, rat orthologue of TRPM8). Agonist at TRPM8 (EC50 = 0.2 µM) and ANKTM1(TRPA1). Agonist effects require Ca2+ and are pH dependent. Icilin induced G1 arrest in PC-3 prostate cancer cells without cell death\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410911371604,"sku":"ABM147162-1","price":106.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410911404372,"sku":"ABM147162-2","price":401.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4380.png?v=1791103620","url":"https:\/\/www.abmium.com\/products\/tribio-icilin-trpm8-channel-activator","provider":"ABMIUM","version":"1.0","type":"link"}