{"product_id":"tribio-clodronate-2na-bis-phosphonate-osteoclast-apoptosis-agent","title":"Clodronate 2Na, Bis-phosphonate; Osteoclast apoptosis agent","description":"\u003cp\u003eClodronate is a first generation non-nitrogenous bisphosphonate drug for the prevention and treatment of osteoporosis and skeletal fractures\/hypercalcemia in patients with cancer. It strongly binds to hydroxyapatite and directly reduces osteoclast activity. Clodronate is metabolized in vitro to a cytotoxic ATP analog (AppCCl2p) which inhibits ADP\/ATP translocase in the mitochondrial inner membrane leading to osteoclast apoptosis\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410899411284,"sku":"ABM146837-1","price":49.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410899444052,"sku":"ABM146837-2","price":114.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4631.png?v=1791103444","url":"https:\/\/www.abmium.com\/products\/tribio-clodronate-2na-bis-phosphonate-osteoclast-apoptosis-agent","provider":"ABMIUM","version":"1.0","type":"link"}